| Reaction Details |
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 | Report a problem with these data |
| Target | Transcriptional regulator ERG |
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| Ligand | BDBM50379275 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_811271 (CHEMBL2015223) |
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| Kd | 11700±n/a nM |
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| Citation |  Kemp, MM; Weïwer, M; Koehler, AN Unbiased binding assays for discovering small-molecule probes and drugs. Bioorg Med Chem20:1979-89 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transcriptional regulator ERG |
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| Name: | Transcriptional regulator ERG |
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| Synonyms: | ERG | ERG_HUMAN | Transforming protein ERG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54615.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1335569 |
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| Residue: | 486 |
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| Sequence: | MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQ
QDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHM
PPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTK
DDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPN
TSVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPY
QILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGE
RKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPS
DLPYMGSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNPYWNSPTGGIYPNTRLPTSHMPS
HLGTYY
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| BDBM50379275 |
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| n/a |
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| Name | BDBM50379275 |
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| Synonyms: | CHEMBL2011500 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13Cl2NO4 |
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| Mol. Mass. | 366.195 |
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| SMILES | COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(Cl)ccc2Cl |
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| Structure | 
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