Reaction Details |
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Target | Protein E6 |
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Ligand | BDBM26658 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_811818 (CHEMBL2014495) |
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IC50 | 4000±n/a nM |
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Citation | Yuan, CH; Filippova, M; Tungteakkhun, SS; Duerksen-Hughes, PJ; Krstenansky, JL Small molecule inhibitors of the HPV16-E6 interaction with caspase 8. Bioorg Med Chem Lett22:2125-9 (2012) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Protein E6 |
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Name: | Protein E6 |
Synonyms: | E6 | VE6_HPV16 |
Type: | PROTEIN |
Mol. Mass.: | 19201.73 |
Organism: | Human papillomavirus type 16 |
Description: | ChEMBL_811818 |
Residue: | 158 |
Sequence: | MHQKRTAMFQDPQERPRKLPQLCTELQTTIHDIILECVYCKQQLLRREVYDFAFRDLCIV
YRDGNPYAVCDKCLKFYSKISEYRHYCYSLYGTTLEQQYNKPLCDLLIRCINCQKPLCPE
EKQRHLDKKQRFHNIRGRWTGRCMSCCRSSRTRRETQL
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BDBM26658 |
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n/a |
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Name | BDBM26658 |
Synonyms: | 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopyran-4-one | 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone | 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one | 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one | CHEMBL28626 | MLS000069618 | Morin (19) | Morin (5) | Morin (Mor) | SMR000058259 | cid_5281670 | morin |
Type | Flavonoid |
Emp. Form. | C15H10O7 |
Mol. Mass. | 302.2357 |
SMILES | Oc1ccc(c(O)c1)-c1oc2cc(O)cc(O)c2c(=O)c1O |
Structure |
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