| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-1 |
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| Ligand | BDBM50379837 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_809737 (CHEMBL2016156) |
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| Ki | 810±n/a nM |
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| Citation |  Liang, G; Chen, X; Aldous, S; Pu, SF; Mehdi, S; Powers, E; Xia, T; Wang, R Human kallikrein 6 inhibitors with a para-amidobenzylanmine P1 group identified through virtual screening. Bioorg Med Chem Lett22:2450-5 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-1 |
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| Name: | Kallikrein-1 |
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| Synonyms: | KLK1 | KLK1_HUMAN | Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein |
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| Type: | Enzyme |
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| Mol. Mass.: | 28874.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06870 |
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| Residue: | 262 |
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| Sequence: | MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
PSVAVRVLSYVKWIEDTIAENS
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| BDBM50379837 |
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| n/a |
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| Name | BDBM50379837 |
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| Synonyms: | CHEMBL2011749 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20Br4N4O2 |
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| Mol. Mass. | 656.004 |
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| SMILES | NC(=N)c1cc(Br)c(OCCCCCOc2c(Br)cc(cc2Br)C(N)=N)c(Br)c1 |
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| Structure | 
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