| Reaction Details |
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 | Report a problem with these data |
| Target | Testis-specific serine/threonine-protein kinase 2 |
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| Ligand | BDBM50362169 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_813710 (CHEMBL2019912) |
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| IC50 | >30000±n/a nM |
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| Citation |  Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors. ACS Med Chem Lett2:632-637 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Testis-specific serine/threonine-protein kinase 2 |
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| Name: | Testis-specific serine/threonine-protein kinase 2 |
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| Synonyms: | DGSG | SPOGA2 | STK22B | TSSK2 | TSSK2_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40954.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1459845 |
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| Residue: | 358 |
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| Sequence: | MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
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| BDBM50362169 |
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| n/a |
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| Name | BDBM50362169 |
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| Synonyms: | CHEMBL1938680 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20ClN3O2 |
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| Mol. Mass. | 381.855 |
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| SMILES | Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1 |
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| Structure | 
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