| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 3 |
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| Ligand | BDBM50380340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_812704 (CHEMBL2019205) |
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| EC50 | >25000±n/a nM |
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| Citation |  Pennington, LD; Sham, KK; Pickrell, AJ; Harrington, PE; Frohn, MJ; Lanman, BA; Reed, AB; Croghan, MD; Lee, MR; Xu, H; McElvain, M; Xu, Y; Zhang, X; Fiorino, M; Horner, M; Morrison, HG; Arnett, HA; Fotsch, C; Wong, M; Cee, VJ 4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1. ACS Med Chem Lett2:752-757 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 3 |
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| Name: | Sphingosine 1-phosphate receptor 3 |
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| Synonyms: | C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42278.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99500 |
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| Residue: | 378 |
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| Sequence: | MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP
SSCIMDKNAALQNGIFCN
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| BDBM50380340 |
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| n/a |
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| Name | BDBM50380340 |
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| Synonyms: | CHEMBL2017803 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22ClN3O2S |
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| Mol. Mass. | 403.926 |
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| SMILES | COc1ccccc1C(=O)NC(=S)Nc1ccc(N2CCCCC2)c(Cl)c1 |
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| Structure | 
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