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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50380918 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_813976 (CHEMBL2020488) | ||
| Ki | 10±n/a nM | ||
| Citation |  Fichtner, M; Lee, E; Tomlinson, E; Scott, D; Cornelius, P; Patterson, TA; Carpino, PA Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor. Bioorg Med Chem Lett22:2738-43 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50380918 | |||
| n/a | |||
| Name | BDBM50380918 | ||
| Synonyms: | CHEMBL2016735 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H25FN4O2 | ||
| Mol. Mass. | 420.4793 | ||
| SMILES | CN([C@H]1CC[C@]2(CC1)OCc1ccccc21)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:2.1,5.8,(2.04,3.76,;2,2.21,;.65,1.48,;.64,-.06,;-.69,-.83,;-2.02,-.05,;-2.02,1.48,;-.69,2.25,;-1.86,-1.59,;-3.27,-2.21,;-4.29,-1.07,;-5.83,-1.06,;-6.6,.26,;-5.84,1.59,;-4.29,1.6,;-3.52,.27,;3.32,1.41,;3.39,-.13,;4.65,2.19,;5.94,1.34,;7.39,1.89,;8.35,.69,;7.5,-.6,;6.02,-.19,;8.26,-1.95,;7.46,-3.27,;8.22,-4.62,;9.76,-4.64,;10.55,-3.3,;9.79,-1.96,;10.58,-.64,)| | ||
| Structure | 
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