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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 ( NPY Y5) | ||
| Ligand | BDBM50380920 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_813976 | ||
| Ki | 2.4±n/a nM | ||
| Citation |  Fichtner M; Lee E; Tomlinson E; Scott D; Cornelius P; Patterson TA; Carpino PA Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor. Bioorg Med Chem Lett 22:2738-43 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 ( NPY Y5) | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPYY5 | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50380920 | |||
| n/a | |||
| Name | BDBM50380920 | ||
| Synonyms: | CHEMBL2016737 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H25FN4O3 | ||
| Mol. Mass. | 448.4894 | ||
| SMILES | CN([C@H]1CC[C@@]2(CC1)Cc1ccccc1C(=O)O2)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:2.1,5.19,(1.18,-5.8,;1.14,-7.34,;-.21,-8.07,;-.22,-9.61,;-1.54,-10.37,;-2.87,-9.6,;-2.88,-8.07,;-1.54,-7.3,;-4.21,-8.83,;-5.53,-9.6,;-6.86,-8.83,;-8.2,-9.59,;-8.2,-11.14,;-6.87,-11.91,;-5.54,-11.15,;-4.2,-11.92,;-4.2,-13.46,;-2.86,-11.14,;2.46,-8.14,;2.52,-9.68,;3.79,-7.36,;5.07,-8.21,;6.52,-7.66,;7.48,-8.86,;6.64,-10.15,;5.15,-9.74,;7.39,-11.49,;6.6,-12.81,;7.35,-14.16,;8.89,-14.18,;9.68,-12.85,;8.92,-11.51,;9.71,-10.18,)| | ||
| Structure | 
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