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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50380926 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_813976 (CHEMBL2020488) | ||
| Ki | 11±n/a nM | ||
| Citation |  Fichtner, M; Lee, E; Tomlinson, E; Scott, D; Cornelius, P; Patterson, TA; Carpino, PA Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor. Bioorg Med Chem Lett22:2738-43 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50380926 | |||
| n/a | |||
| Name | BDBM50380926 | ||
| Synonyms: | CHEMBL2016743 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H28N4O3 | ||
| Mol. Mass. | 456.5362 | ||
| SMILES | CCN([C@H]1CC[C@@]2(CC1)Cc1ccccc1C(=O)O2)C(=O)Nc1cnc(cn1)-c1ccccc1 |r,wU:3.2,6.20,(-.27,-8.96,;1.04,-9.76,;1,-11.3,;-.35,-12.04,;-.36,-13.58,;-1.68,-14.34,;-3.01,-13.57,;-3.02,-12.03,;-1.68,-11.27,;-4.35,-12.8,;-5.67,-13.57,;-7,-12.8,;-8.34,-13.56,;-8.34,-15.11,;-7.01,-15.88,;-5.68,-15.11,;-4.34,-15.88,;-4.34,-17.42,;-3,-15.11,;2.32,-12.11,;2.39,-13.65,;3.65,-11.33,;4.99,-12.08,;6.32,-11.31,;7.65,-12.08,;7.65,-13.62,;6.32,-14.4,;4.98,-13.63,;8.99,-14.39,;8.99,-15.94,;10.32,-16.71,;11.66,-15.93,;11.65,-14.38,;10.32,-13.62,)| | ||
| Structure | 
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