| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50381886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_817534 (CHEMBL2027757) |
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| Ki | 0.25±n/a nM |
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| Citation |  Manera, C; Saccomanni, G; Malfitano, AM; Bertini, S; Castelli, F; Laezza, C; Ligresti, A; Lucchesi, V; Tuccinardi, T; Rizzolio, F; Bifulco, M; Di Marzo, V; Giordano, A; Macchia, M; Martinelli, A Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold. Eur J Med Chem52:284-94 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50381886 |
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| n/a |
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| Name | BDBM50381886 |
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| Synonyms: | CHEMBL2022363 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25FN2O2 |
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| Mol. Mass. | 392.4659 |
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| SMILES | Fc1ccc(Cn2c3ccccc3cc(C(=O)NC3CCCCCC3)c2=O)cc1 |
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| Structure | 
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