| Reaction Details |
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 | Report a problem with these data |
| Target | 2-Hydroxyacid oxidase 1 |
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| Ligand | BDBM50382412 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_815423 (CHEMBL2027075) |
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| IC50 | 45700±n/a nM |
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| Citation |  Barawkar, DA; Meru, A; Bandyopadhyay, A; Banerjee, A; Deshpande, AM; Athare, C; Koduru, C; Khose, G; Gundu, J; Mahajan, K; Patil, P; Kandalkar, SR; Niranjan, S; Bhosale, S; De, S; Mukhopadhyay, S; Chaudhary, S; Koul, S; Singh, U; Chugh, A; Palle, VP; Mookhtiar, KA; Vacca, J; Chakravarty, PK; Nargund, RP; Wright, SD; Roy, S; Graziano, MP; Singh, SB; Cully, D; Cai, TQ Potent and Selective Inhibitors of Long Chain l-2-Hydroxy Acid Oxidase Reduced Blood Pressure in DOCA Salt-Treated Rats. ACS Med Chem Lett2:919-923 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-Hydroxyacid oxidase 1 |
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| Name: | 2-Hydroxyacid oxidase 1 |
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| Synonyms: | Hao1 | Hao1_mapped | Hydroxyacid oxidase 1 | Hydroxyacid oxidase 1 (Mapped) | Protein Hao1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40969.82 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_815423 |
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| Residue: | 370 |
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| Sequence: | MLPRLVCISDYEQHARTVLQKSVYDYYKSGANDQETLADNIRAFSRWKLYPRMLRNVADI
DLSTSVLGQRVSMPICVGATAMQCMAHVDGELATVRACQTMGTGMMLSSWATSSIEEVAE
AGPEALRWMQLYIYKDREVSSQLVKRAEQMGYKAIFVTVDTPYLGNRFDDVRNRFKLPPQ
LRMKNFETNDLAFSPKGNFGDNSGLAEYVAQAIDPSLSWDDIKWLRRLTSLPIVVKGILR
GDDAQEAVKHGVDGILVSNHGARQLDGVPATIDALPEIVEAVEGKVEVFLDGGVRKGTDV
LKALALGARAVFVGRPIIWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV
RKNPLAVSKI
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| BDBM50382412 |
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| n/a |
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| Name | BDBM50382412 |
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| Synonyms: | CHEMBL2022570 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15FN2O2 |
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| Mol. Mass. | 310.3223 |
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| SMILES | Cc1[nH]nc(C(O)=O)c1Cc1cccc(c1)-c1ccc(F)cc1 |
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| Structure | 
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