| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50382980 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_818419 (CHEMBL2034646) |
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| Ki | 1230.27±n/a nM |
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| Citation |  Langmead, CJ; Andrews, SP; Congreve, M; Errey, JC; Hurrell, E; Marshall, FH; Mason, JS; Richardson, CM; Robertson, N; Zhukov, A; Weir, M Identification of novel adenosine A(2A) receptor antagonists by virtual screening. J Med Chem55:1904-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50382980 |
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| n/a |
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| Name | BDBM50382980 |
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| Synonyms: | CHEMBL2030682 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18FN3O3 |
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| Mol. Mass. | 367.3736 |
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| SMILES | COCCN1C(c2c(n[nH]c2C1=O)-c1ccccc1O)c1ccc(F)cc1 |
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| Structure | 
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