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TargetAdenosine receptor A2a
LigandBDBM50382984
Substrate/Competitorn/a
Meas. Tech.ChEMBL_818419
Ki 3.09±n/a nM
Citation Langmead CJAndrews SPCongreve MErrey JCHurrell EMarshall FHMason JSRichardson CMRobertson NZhukov AWeir M Identification of novel adenosine A(2A) receptor antagonists by virtual screening. J Med Chem 55:1904-9 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A2a
Name:Adenosine receptor A2a
Synonyms:A2A adenosine receptor (hA2A) | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44716.46
Organism:Homo sapiens (Human)
Description:P29274
Residue:412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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  Blast E-value cutoff:
BDBM50382984
n/a
NameBDBM50382984
Synonyms:CHEMBL2030687
TypeSmall organic molecule
Emp. Form.C18H17NO4S
Mol. Mass.343.397
SMILESCCCc1cc2c(cc1OC(C)=O)occ(-c1nc(C)cs1)c2=O
Structure
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