| Reaction Details |
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 | Report a problem with these data |
| Target | Relaxin-3 receptor 2 |
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| Ligand | BDBM50382992 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_818422 (CHEMBL2034649) |
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| IC50 | 7.94±n/a nM |
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| Citation |  Shabanpoor, F; Akhter Hossain, M; Ryan, PJ; Belgi, A; Layfield, S; Kocan, M; Zhang, S; Samuel, CS; Gundlach, AL; Bathgate, RA; Separovic, F; Wade, JD Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1. J Med Chem55:1671-81 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Relaxin-3 receptor 2 |
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| Name: | Relaxin-3 receptor 2 |
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| Synonyms: | G-protein coupled receptor 100 | G-protein coupled receptor GPCR142 | GPCR142 | GPR100 | Insulin-like peptide INSL5 receptor | RL3R2_HUMAN | RLN3 receptor 2 | RLN3R2 | RXFP4 | Relaxin family peptide receptor 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41161.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1456194 |
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| Residue: | 374 |
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| Sequence: | MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFG
VEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQD
SRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHS
NSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGRRWVASNPRESR
PSTLLTNLDRGTPG
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| BDBM50382992 |
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| n/a |
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| Name | BDBM50382992 |
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| Synonyms: | CHEMBL2030701 |
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| Type | Small organic molecule |
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| Emp. Form. | C166H262N50O46S4 |
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| Mol. Mass. | 3822.424 |
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| SMILES | n/a |
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| Structure | 
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