| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50383004 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_818429 (CHEMBL2034749) |
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| IC50 | 3.1±n/a nM |
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| Citation |  Taliani, S; Pugliesi, I; Barresi, E; Simorini, F; Salerno, S; La Motta, C; Marini, AM; Cosimelli, B; Cosconati, S; Di Maro, S; Marinelli, L; Daniele, S; Trincavelli, ML; Greco, G; Novellino, E; Martini, C; Da Settimo, F 3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists. J Med Chem55:1490-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50383004 |
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| n/a |
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| Name | BDBM50383004 |
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| Synonyms: | CHEMBL2030707 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H13ClN4O |
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| Mol. Mass. | 372.807 |
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| SMILES | Clc1ccc2n(-c3ccccc3)c3nnc(-c4ccccc4)c(=O)n3c2c1 |
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| Structure | 
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