| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50383372 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_818053 (CHEMBL2033581) |
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| IC50 | >500±n/a nM |
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| Citation |  Lieber, S; Scheer, F; Meissner, W; Naruhn, S; Adhikary, T; Müller-Brüsselbach, S; Diederich, WE; Müller, R (Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): an orally bioavailable PPARß/d-selective ligand with inverse agonistic properties. J Med Chem55:2858-68 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NUC1 | Nr1c2 | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR-beta | PPAR-delta | PPARD_MOUSE | Pparb | Ppard |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49719.14 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1288931 |
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| Residue: | 440 |
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| Sequence: | MEQPQEETPEAREEEKEEVAMGDGAPELNGGPEHTLPSSSCADLSQNSSPSSLLDQLQMG
CDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCDRICKIQKKN
RNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQHNPQLADLKAFSKH
IYNAYLKNFNMTKKKARSILTGKSSHNAPFVIHDIETLWQAEKGLVWKQLVNGLPPYNEI
SVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKD
GLLVANGSGFVTHEFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDR
PGLMNVPQVEAIQDTILRALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLK
KTESETLLHPLLQEIYKDMY
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| BDBM50383372 |
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| n/a |
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| Name | BDBM50383372 |
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| Synonyms: | CHEMBL1998001 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16N2 |
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| Mol. Mass. | 248.3223 |
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| SMILES | CN(C)c1ccc(\C=C(/C#N)c2ccccc2)cc1 |
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| Structure | 
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