| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase |
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| Ligand | BDBM50383970 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_819737 (CHEMBL2034167) |
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| IC50 | 1.1±n/a nM |
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| Citation |  Axten, JM; Medina, JR; Blackledge, CW; Duquenne, C; Grant, SW; Bobko, MA; Peng, T; Miller, WH; Pinckney, T; Gallagher, TF; Kulkarni, S; Lewandowski, T; Van Aller, GS; Zonis, R; Ward, P; Campobasso, N Acylprolinamides: a new class of peptide deformylase inhibitors with in vivo antibacterial activity. Bioorg Med Chem Lett22:4028-32 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptide deformylase |
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| Name: | Peptide deformylase |
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| Synonyms: | DEF_STRPN | PDF | Polypeptide deformylase | def |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22668.24 |
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| Organism: | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) |
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| Description: | ChEMBL_819737 |
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| Residue: | 203 |
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| Sequence: | MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEIILGEKMMQFLKHSQDPV
MAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEAYDLEAIMYNPKIVSHSVQ
DAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHRIKLKGYNSIVVQHEIDHING
IMFYDRINEKDPFAVKDGLLILE
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| BDBM50383970 |
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| n/a |
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| Name | BDBM50383970 |
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| Synonyms: | CHEMBL2032144 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H30N4O6 |
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| Mol. Mass. | 398.454 |
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| SMILES | OCCNC(=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1CCCC1)CN(O)C=O |r| |
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| Structure | 
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