| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP3 subtype |
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| Ligand | BDBM50384444 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_821762 (CHEMBL2039059) |
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| Ki | 3.16±n/a nM |
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| Citation |  Jin, J; Morales-Ramos, A; Eidam, P; Mecom, J; Li, Y; Brooks, C; Hilfiker, M; Zhang, D; Wang, N; Shi, D; Tseng, PS; Wheless, K; Budzik, B; Evans, K; Jaworski, JP; Jugus, J; Leon, L; Wu, C; Pullen, M; Karamshi, B; Rao, P; Ward, E; Laping, N; Evans, C; Leach, C; Holt, D; Su, X; Morrow, D; Fries, H; Thorneloe, K; Edwards, R Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists. ACS Med Chem Lett1:316-320 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP3 subtype |
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| Name: | Prostaglandin E2 receptor EP3 subtype |
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| Synonyms: | PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 43335.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43115 |
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| Residue: | 390 |
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| Sequence: | MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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| BDBM50384444 |
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| n/a |
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| Name | BDBM50384444 |
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| Synonyms: | CHEMBL2035510 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17FN2O4 |
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| Mol. Mass. | 380.3691 |
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| SMILES | CC(C)C1(OC(=O)NC1=O)c1ccc([nH]c1=O)-c1ccc2cccc(F)c2c1 |
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| Structure | 
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