| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor 2 |
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| Ligand | BDBM50384516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_821892 (CHEMBL2039538) |
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| Ki | 2.5±n/a nM |
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| Citation |  Crosignani, S; Jorand-Lebrun, C; Campbell, G; Prêtre, A; Grippi-Vallotton, T; Quattropani, A; Bouscary-Desforges, G; Bombrun, A; Missotten, M; Humbert, Y; Frémaux, C; Pâquet, M; El Harkani, K; Bradshaw, CG; Cleva, C; Abla, N; Daff, H; Schott, O; Pittet, PA; Arrighi, JF; Gaudet, M; Johnson, Z Discovery of a Novel Series of CRTH2 (DP2) Receptor Antagonists Devoid of Carboxylic Acids. ACS Med Chem Lett2:938-942 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor 2 |
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| Name: | Prostaglandin D2 receptor 2 |
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| Synonyms: | CD_antigen=CD294 | CRTH2 | Chemoattractant Receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) | Chemoattractant receptor-homologous molecule expressed on Th2 cells | Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | DL1R | G protein-coupled receptor 44 | G-protein coupled receptor 44 | GPR44 | PD2R2_HUMAN | PTGDR2 | Prostaglandin D2 | Prostaglandin D2 receptor 2 | Prostaglandin D2 receptor 2 (PGD2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 43295.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y5Y4 |
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| Residue: | 395 |
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| Sequence: | MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCR
MRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGF
LLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRI
MCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRR
PGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVAN
PVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRP
EEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
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| BDBM50384516 |
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| n/a |
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| Name | BDBM50384516 |
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| Synonyms: | CHEMBL2036226 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24FN5O3S |
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| Mol. Mass. | 493.553 |
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| SMILES | Cc1ccc(CCC(=O)N(Cc2ccc(cc2)S(C)(=O)=O)c2cc(F)cc(c2)-c2nnn[nH]2)cc1 |
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| Structure | 
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