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TargetRegulator of G-protein signaling 8
LigandBDBM50384756
Substrate/Competitorn/a
Meas. Tech.ChEMBL_821036
IC50 17500±n/a nM
Citation Turner EMBlazer LLNeubig RRHusbands SM Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins. ACS Med Chem Lett 3:146-150 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Regulator of G-protein signaling 8
Name:Regulator of G-protein signaling 8
Synonyms:Regulator of G-protein signaling 8 (RGS8)
Type:Enzyme Catalytic Domain
Mol. Mass.:20925.80
Organism:Homo sapiens (Human)
Description:gi_74355113
Residue:180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50384756
n/a
NameBDBM50384756
Synonyms:CHEMBL2037353
TypeSmall organic molecule
Emp. Form.C16H13ClN2O2S
Mol. Mass.332.805
SMILESCc1ccc(cc1)-n1sc(=O)n(Cc2cccc(Cl)c2)c1=O
Structure
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