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TargetGlycylpeptide N-tetradecanoyltransferase 2
LigandBDBM50384911
Substrate/Competitorn/a
Meas. Tech.ChEMBL_820573 (CHEMBL2040310)
Ki 23230±n/a nM
Citation Goncalves, VBrannigan, JAWhalley, DAnsell, KHSaxty, BHolder, AAWilkinson, AJTate, EWLeatherbarrow, RJ Discovery of Plasmodium vivax N-myristoyltransferase inhibitors: screening, synthesis, and structural characterization of their binding mode. J Med Chem55:3578-82 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Glycylpeptide N-tetradecanoyltransferase 2
Name:Glycylpeptide N-tetradecanoyltransferase 2
Synonyms:Glycylpeptide N-tetradecanoyltransferase 2 | Myristoyl-CoA:protein N-myristoyltransferase 2 | NMT 2 | NMT2 | NMT2_HUMAN | Peptide N-myristoyltransferase 2 | Type II N-myristoyltransferase
Type:PROTEIN
Mol. Mass.:56986.61
Organism:Homo sapiens (Human)
Description:ChEMBL_1435042
Residue:498
Sequence:
MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGYLGAKKKKKKQKRKKEKPN
SGGTKSDSASDSQEIKIQQPSKNPSVPMQKLQDIQRAMELLSACQGPARNIDEAAKHRYQ
FWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNE
NYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDS
VKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRYWH
RSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTYLK
QFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKA
AYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYL
YNWRCPGTDSEKVGLVLQ
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BDBM50384911
n/a
NameBDBM50384911
Synonyms:CHEMBL2036500
TypeSmall organic molecule
Emp. Form.C16H18N2OS
Mol. Mass.286.392
SMILESCCc1c(C)nc2ccc(OC)cc2c1SCCC#N
Structure
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