| Reaction Details |
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 | Report a problem with these data |
| Target | Glycylpeptide N-tetradecanoyltransferase 2 |
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| Ligand | BDBM50384913 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_820573 (CHEMBL2040310) |
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| Ki | >100000±n/a nM |
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| Citation |  Goncalves, V; Brannigan, JA; Whalley, D; Ansell, KH; Saxty, B; Holder, AA; Wilkinson, AJ; Tate, EW; Leatherbarrow, RJ Discovery of Plasmodium vivax N-myristoyltransferase inhibitors: screening, synthesis, and structural characterization of their binding mode. J Med Chem55:3578-82 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycylpeptide N-tetradecanoyltransferase 2 |
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| Name: | Glycylpeptide N-tetradecanoyltransferase 2 |
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| Synonyms: | Glycylpeptide N-tetradecanoyltransferase 2 | Myristoyl-CoA:protein N-myristoyltransferase 2 | NMT 2 | NMT2 | NMT2_HUMAN | Peptide N-myristoyltransferase 2 | Type II N-myristoyltransferase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56986.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1435042 |
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| Residue: | 498 |
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| Sequence: | MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGYLGAKKKKKKQKRKKEKPN
SGGTKSDSASDSQEIKIQQPSKNPSVPMQKLQDIQRAMELLSACQGPARNIDEAAKHRYQ
FWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNE
NYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDS
VKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRYWH
RSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTYLK
QFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKA
AYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYL
YNWRCPGTDSEKVGLVLQ
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| BDBM50384913 |
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| n/a |
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| Name | BDBM50384913 |
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| Synonyms: | CHEMBL2036501 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N2OS |
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| Mol. Mass. | 258.339 |
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| SMILES | COc1ccc2nc(C)cc(SCCC#N)c2c1 |
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| Structure | 
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