| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50384954 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_820695 (CHEMBL2037966) |
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| Ki | 0.8±n/a nM |
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| Citation |  Zhu, XY; Etukala, JR; Eyunni, SV; Setola, V; Roth, BL; Ablordeppey, SY Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): a search for new dual-acting agents as potential antidepressants. Eur J Med Chem53:124-32 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41307.65 |
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| Organism: | RAT |
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| Description: | DOPAMINE D4.4 0 RAT::P30729 |
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| Residue: | 387 |
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| Sequence: | MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASER
ILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASI
FNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVC
CLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPV
SDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRK
RGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVN
SALNPIIYTIFNAEFRSVFRKTLRLRC
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| BDBM50384954 |
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| n/a |
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| Name | BDBM50384954 |
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| Synonyms: | CHEMBL2037521 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23N5S |
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| Mol. Mass. | 353.484 |
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| SMILES | C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1 |
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| Structure | 
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