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TargetProstaglandin E2 receptor EP4 subtype
LigandBDBM50385141
Substrate/Competitorn/a
Meas. Tech.ChEMBL_822929 (CHEMBL2038100)
Ki 0.35±n/a nM
Citation Kambe, TMaruyama, TNakai, YOida, HMaruyama, TAbe, NNishiura, ANakai, HToda, M Synthesis and evaluation of¿-lactam analogs of PGE2 as EP4 and EP2/EP4 agonists. Bioorg Med Chem20:3502-22 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP4 subtype
Name:Prostaglandin E2 receptor EP4 subtype
Synonyms:PE2R4_MOUSE | PGE receptor, EP4 subtype | Prostanoid EP4 receptor | Ptger4 | Ptgerep4
Type:G-protein coupled receptor
Mol. Mass.:56175.66
Organism:Mus musculus (Mouse)
Description:n/a
Residue:513
Sequence:
MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGN
LVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYS
TFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPN
MGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHR
QFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVI
LLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILL
RKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTS
QTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVD
EVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50385141
n/a
NameBDBM50385141
Synonyms:CHEMBL2036321
TypeSmall organic molecule
Emp. Form.C28H30N2O4S2
Mol. Mass.522.679
SMILESCc1ccc(cc1C)-c1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r|
Structure
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