| Reaction Details |
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 | Report a problem with these data |
| Target | Penicillin-binding protein 2X |
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| Ligand | BDBM50385263 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_822530 (CHEMBL2039463) |
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| IC50 | 262000±n/a nM |
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| Citation |  Zervosen, A; Bouillez, A; Herman, A; Amoroso, A; Joris, B; Sauvage, E; Charlier, P; Luxen, A Synthesis and evaluation of boronic acids as inhibitors of Penicillin Binding Proteins of classes A, B and C. Bioorg Med Chem20:3915-24 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Penicillin-binding protein 2X |
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| Name: | Penicillin-binding protein 2X |
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| Synonyms: | PBP-2X | PBP2X | PBPX_STRR6 | pbpX |
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| Type: | PROTEIN |
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| Mol. Mass.: | 82337.09 |
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| Organism: | Streptococcus pneumoniae R6 |
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| Description: | ChEMBL_822530 |
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| Residue: | 750 |
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| Sequence: | MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAK
EAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFN
KVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDF
TTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDR
LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGE
ILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFN
SSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFK
FGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI
SAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVP
GQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQL
GEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQP
IVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEF
QGSGSTVQKQDVRANTAIKDIKKITLTLGD
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| BDBM50385263 |
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| n/a |
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| Name | BDBM50385263 |
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| Synonyms: | CHEMBL2035289 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H9BClNO3 |
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| Mol. Mass. | 213.426 |
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| SMILES | OB(O)CNC(=O)c1ccccc1Cl |
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| Structure | 
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