| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 4 |
|---|
| Ligand | BDBM50385612 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_825943 (CHEMBL2044967) |
|---|
| IC50 | 11±n/a nM |
|---|
| Citation |  Inokuchi, E; Oishi, S; Kubo, T; Ohno, H; Shimura, K; Matsuoka, M; Fujii, N Potent CXCR4 antagonists containing amidine type Peptide bond isosteres. ACS Med Chem Lett2:477-480 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-X-C chemokine receptor type 4 |
|---|
| Name: | C-X-C chemokine receptor type 4 |
|---|
| Synonyms: | C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4) | CD_antigen=CD184 | CXC-R4 | CXCR-4 | CXCR4 | CXCR4_HUMAN | FB22 | Fusin | HM89 | LCR1 | LESTR | Leukocyte-derived seven transmembrane domain receptor | NPYRL | SDF-1 receptor | Stromal cell-derived factor 1 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39754.61 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P61073 |
|---|
| Residue: | 352 |
|---|
| Sequence: | MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVI
LVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNL
YSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEA
DDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKT
TVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPI
LYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
|
|
|
|---|
| BDBM50385612 |
|---|
| n/a |
|---|
| Name | BDBM50385612 |
|---|
| Synonyms: | CHEMBL2042120 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C36H48N12O5 |
|---|
| Mol. Mass. | 728.8437 |
|---|
| SMILES | [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6@@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc3ccccc3c2)-[#7]=[#6](-[#7])-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6]-1=O |r,w:40.43| |
|---|
| Structure | 
|
|---|
Search and Browse
