| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 14 |
|---|
| Ligand | BDBM50385647 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_823429 (CHEMBL2046097) |
|---|
| IC50 | 813±n/a nM |
|---|
| Citation |  Dyrager, C; Möllers, LN; Kjäll, LK; Alao, JP; Dinér, P; Wallner, FK; Sunnerhagen, P; Grøtli, M Design, synthesis, and biological evaluation of chromone-based p38 MAP kinase inhibitors. J Med Chem54:7427-31 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mitogen-activated protein kinase 14 |
|---|
| Name: | Mitogen-activated protein kinase 14 |
|---|
| Synonyms: | CSAID-binding protein | CSBP | CSBP1 | CSBP2 | CSPB1 | Cytokine suppressive anti-inflammatory drug-binding protein | MAP kinase 14 | MAP kinase MXI2 | MAP kinase p38 alpha | MAPK 14 | MAPK14 | MAX-interacting protein 2 | MK14_HUMAN | MXI2 | Mitogen-activated protein kinase p38 alpha | SAPK2A | Stress-activated protein kinase 2a | p38 MAP kinase alpha/beta |
|---|
| Type: | Serine/threonine-protein kinase |
|---|
| Mol. Mass.: | 41286.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q16539 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
|
|
|
|---|
| BDBM50385647 |
|---|
| n/a |
|---|
| Name | BDBM50385647 |
|---|
| Synonyms: | CHEMBL2041956 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H12FNO2 |
|---|
| Mol. Mass. | 317.3132 |
|---|
| SMILES | Fc1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccncc1 |
|---|
| Structure | 
|
|---|
Search and Browse
