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TargetMuscarinic acetylcholine receptor M2
LigandBDBM50385680
Substrate/Competitorn/a
Meas. Tech.ChEMBL_826079
Ki 6456.54±n/a nM
Citation Del Bello FBarocelli EBertoni SBonifazi ACamalli MCampi GGiannella MMatucci RNesi MPigini MQuaglia WPiergentili A 1,4-dioxane, a suitable scaffold for the development of novel M3 muscarinic receptor antagonists. J Med Chem 55:1783-7 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Muscarinic acetylcholine receptor M2
Name:Muscarinic acetylcholine receptor M2 and M5
Synonyms:CHRM2 | Cholinergic, muscarinic M2 | RecName: Full=Muscarinic acetylcholine receptor M2
Type:GPCR
Mol. Mass.:51730.61
Organism:Homo sapiens (Human)
Description:P08172
Residue:466
Sequence:
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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  Blast E-value cutoff:
BDBM50385680
n/a
NameBDBM50385680
Synonyms:CHEMBL2042402
TypeSmall organic molecule
Emp. Form.C14H22NO2
Mol. Mass.236.3294
SMILESC[N+](C)(C)C[C@@H]1COC[C@@H](O1)c1ccccc1 |r|
Structure
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