| Reaction Details |
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 | Report a problem with these data |
| Target | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
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| Ligand | BDBM50386133 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_824644 (CHEMBL2045702) |
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| IC50 | 64000±n/a nM |
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| Citation |  Jadhav, RD; Kadam, KS; Kandre, S; Guha, T; Reddy, MM; Brahma, MK; Deshmukh, NJ; Dixit, A; Doshi, L; Potdar, N; Enose, AA; Vishwakarma, RA; Sivaramakrishnan, H; Srinivasan, S; Nemmani, KV; Gupte, A; Gangopadhyay, AK; Sharma, R Synthesis and biological evaluation of isoxazole, oxazole, and oxadiazole containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors. Eur J Med Chem54:324-42 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
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| Name: | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
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| Synonyms: | Beta4GalNAcT-1 | CGAT1_HUMAN | CHGN | CSGALNACT1 | Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 | CsGalNAcT-1 | GALNACT1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61307.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_824644 |
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| Residue: | 532 |
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| Sequence: | MMMVRRGLLAWISRVVVLLVLLCCAISVLYMLACTPKGDEEQLALPRANSPTGKEGYQAV
LQEWEEQHRNYVSSLKRQIAQLKEELQERSEQLRNGQYQASDAAGLGLDRSPPEKTQADL
LAFLHSQVDKAEVNAGVKLATEYAAVPFDSFTLQKVYQLETGLTRHPEEKPVRKDKRDEL
VEAIESALETLNSPAENSPNHRPYTASDFIEGIYRTERDKGTLYELTFKGDHKHEFKRLI
LFRPFGPIMKVKNEKLNMANTLINVIVPLAKRVDKFRQFMQNFREMCIEQDGRVHLTVVY
FGKEEINEVKGILENTSKAANFRNFTFIQLNGEFSRGKGLDVGARFWKGSNVLLFFCDVD
IYFTSEFLNTCRLNTQPGKKVFYPVLFSQYNPGIIYGHHDAVPPLEQQLVIKKETGFWRD
FGFGMTCQYRSDFINIGGFDLDIKGWGGEDVHLYRKYLHSNLIVVRTPVRGLFHLWHEKR
CMDELTPEQYKMCMQSKAMNEASHGQLGMLVFRHEIEAHLRKQKQKTSSKKT
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| BDBM50386133 |
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| n/a |
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| Name | BDBM50386133 |
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| Synonyms: | CHEMBL2042334 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24N4O6 |
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| Mol. Mass. | 452.4599 |
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| SMILES | COc1ccc(NC(=O)Nc2ccc(cc2)-c2cc(on2)C(=O)N[C@@H](C(C)C)C(O)=O)cc1 |r| |
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| Structure | 
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