| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-6 |
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| Ligand | BDBM50386417 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_826901 (CHEMBL2051716) |
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| IC50 | 8200±n/a nM |
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| Citation |  Liang, G; Chen, X; Aldous, S; Pu, SF; Mehdi, S; Powers, E; Giovanni, A; Kongsamut, S; Xia, T; Zhang, Y; Wang, R; Gao, Z; Merriman, G; McLean, LR; Morize, I Virtual Screening and X-ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 Group. ACS Med Chem Lett3:159-164 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-6 |
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| Name: | Kallikrein-6 |
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| Synonyms: | KLK6 | KLK6_HUMAN | Kallikrein 6 | PRSS18 | PRSS9 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26861.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_826901 |
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| Residue: | 244 |
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| Sequence: | MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA
AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE
LIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNM
LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT
IQAK
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| BDBM50386417 |
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| n/a |
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| Name | BDBM50386417 |
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| Synonyms: | CHEMBL2047315 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N4O4S2 |
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| Mol. Mass. | 472.58 |
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| SMILES | COc1ccc2ccc(cc2c1)S(=O)(=O)N(C)[C@H]1CCN(Cc2ccc(s2)C(N)=N)C1=O |r| |
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| Structure | 
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