| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50386718 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_826608 (CHEMBL2050862) |
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| Ki | 7±n/a nM |
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| Citation |  Gitto, R; Damiano, FM; Mader, P; De Luca, L; Ferro, S; Supuran, CT; Vullo, D; Brynda, J; Rezácová, P; Chimirri, A Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors. J Med Chem55:3891-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50386718 |
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| n/a |
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| Name | BDBM50386718 |
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| Synonyms: | CHEMBL2048920 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21N3O6S2 |
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| Mol. Mass. | 427.495 |
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| SMILES | COc1cc2CCN(C(c3ccc(cc3)S(N)(=O)=O)c2cc1OC)S(N)(=O)=O |
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| Structure | 
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