| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vesicular acetylcholine transporter |
|---|
| Ligand | BDBM50018094 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_828202 (CHEMBL2050134) |
|---|
| Ki | 15.2±n/a nM |
|---|
| Citation |  Tu, Z; Wang, W; Cui, J; Zhang, X; Lu, X; Xu, J; Parsons, SM Synthesis and evaluation of in vitro bioactivity for vesicular acetylcholine transporter inhibitors containing two carbonyl groups. Bioorg Med Chem20:4422-9 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vesicular acetylcholine transporter |
|---|
| Name: | Vesicular acetylcholine transporter |
|---|
| Synonyms: | SLC18A3 | Solute carrier family 18 member 3 | VACHT | VACHT_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56900.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1507628 |
|---|
| Residue: | 532 |
|---|
| Sequence: | MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
|
|
|
|---|
| BDBM50018094 |
|---|
| n/a |
|---|
| Name | BDBM50018094 |
|---|
| Synonyms: | (1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol | 2-(4-Phenyl-piperidin-1-yl)-cyclohexanol | 2-(4-Phenyl-piperidin-1-yl)-cyclohexanol(Vesamicol) | CHEMBL20730 | Vesamicol | trans-2-(4-phenylpiperidin-1-yl)cyclohexanol |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H25NO |
|---|
| Mol. Mass. | 259.3865 |
|---|
| SMILES | O[C@@H]1CCCC[C@H]1N1CCC(CC1)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
