| Reaction Details |
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 | Report a problem with these data |
| Target | Protein arginine N-methyltransferase 1 [11-371] |
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| Ligand | BDBM50387478 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_828306 (CHEMBL2050325) |
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| IC50 | 12000±n/a nM |
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| Citation |  Sinha, SH; Owens, EA; Feng, Y; Yang, Y; Xie, Y; Tu, Y; Henary, M; Zheng, YG Synthesis and evaluation of carbocyanine dyes as PRMT inhibitors and imaging agents. Eur J Med Chem54:647-59 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein arginine N-methyltransferase 1 [11-371] |
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| Name: | Protein arginine N-methyltransferase 1 [11-371] |
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| Synonyms: | ANM1_HUMAN | HMT2 | HRMT1L2 | IR1B4 | PRMT1 | Protein arginine N-methyltransferase 1 (PRMT1) | Protein arginine methyltransferase 1 (PRMT1) | Protein-arginine N-methyltransferase 1 |
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| Type: | Protein |
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| Mol. Mass.: | 41506.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99873[11-371] |
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| Residue: | 361 |
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| Sequence: | MENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDE
VRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIV
KANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGL
IFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNAC
LIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYT
HWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRM
R
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| BDBM50387478 |
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| n/a |
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| Name | BDBM50387478 |
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| Synonyms: | CHEMBL2046454 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H33N2 |
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| Mol. Mass. | 457.628 |
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| SMILES | CCCCn1c2cccc3cccc(c23)\c1=C\[CH+]\C=c1/n(CCCC)c2cccc3cccc1c23 |
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| Structure | 
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