| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphoethanolamine N-methyltransferase |
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| Ligand | BDBM50041457 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_829173 (CHEMBL2059995) |
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| IC50 | 1350000±n/a nM |
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| Citation |  Lee, SG; Alpert, TD; Jez, JM Crystal structure of phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with amodiaquine. Bioorg Med Chem Lett22:4990-3 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphoethanolamine N-methyltransferase |
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| Name: | Phosphoethanolamine N-methyltransferase |
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| Synonyms: | PMT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31038.21 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_829173 |
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| Residue: | 266 |
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| Sequence: | MTLIENLNSDKTFLENNQYTDEGVKVYEFIFGENYISSGGLEATKKILSDIELNENSKVL
DIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNNKIIFEANDILTKEFPENN
FDLIYSRDAILHLSLENKNKLFQKCYKWLKPTGTLLITDYCATEKENWDDEFKEYVKQRK
YTLITVEEYADILTACNFKNVVSKDLSDYWNQLLEVEHKYLHENKEEFLKLFSEKKFISL
DDGWSRKIKDSKRKMQRWGYFKATKN
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| BDBM50041457 |
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| n/a |
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| Name | BDBM50041457 |
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| Synonyms: | 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol | AMODIAQUINE | CHEMBL682 | med.21724, Compound 188 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22ClN3O |
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| Mol. Mass. | 355.861 |
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| SMILES | CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O |
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| Structure | 
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