Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetLysophosphatidic acid receptor 5 (LPA5)
LigandBDBM50373826
Substrate/Competitorn/a
Meas. Tech.ChEMBL_830365
IC50>30000±n/a nM
Citation Kozian DHEvers AFlorian PWonerow PJoho SNazare M Selective non-lipid modulator of LPA5 activity in human platelets. Bioorg Med Chem Lett 22:5239-43 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Lysophosphatidic acid receptor 5 (LPA5)
Name:Lysophosphatidic acid receptor 5 (LPA5)
Synonyms:Lysophosphatidic acid receptor 5
Type:Enzyme
Mol. Mass.:41372.36
Organism:Homo sapiens (Human)
Description:Q9H1C0
Residue:372
Sequence:
MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVY
MCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRY
AAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFS
DELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANL
VIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFS
AEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSL
SSFTQCPQDSAL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50373826
n/a
NameBDBM50373826
Synonyms:CHEMBL256470
TypeSmall organic molecule
Emp. Form.C20H23Cl2N5O2S2
Mol. Mass.500.465
SMILESC[C@@H](CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(Cl)c1)Nc1ncnc2c(C)csc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: