| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase FKBP4 |
|---|
| Ligand | BDBM50388279 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_829706 (CHEMBL2061146) |
|---|
| IC50 | 15690±n/a nM |
|---|
| Citation |  Gopalakrishnan, R; Kozany, C; Wang, Y; Schneider, S; Hoogeland, B; Bracher, A; Hausch, F Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52. J Med Chem55:4123-31 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peptidyl-prolyl cis-trans isomerase FKBP4 |
|---|
| Name: | Peptidyl-prolyl cis-trans isomerase FKBP4 |
|---|
| Synonyms: | FK506 binding protein 4 | FKBP4 | FKBP4_HUMAN | FKBP52 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 51793.87 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_154482 |
|---|
| Residue: | 459 |
|---|
| Sequence: | MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW
LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP
KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD
KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN
AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL
EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG
EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE
EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA
|
|
|
|---|
| BDBM50388279 |
|---|
| n/a |
|---|
| Name | BDBM50388279 |
|---|
| Synonyms: | CHEMBL2058233 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H34BrNO9S |
|---|
| Mol. Mass. | 676.572 |
|---|
| SMILES | COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2cccc(Br)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| |
|---|
| Structure | 
|
|---|
Search and Browse
