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TargetFK506 binding protein 4
LigandBDBM23334
Substrate/Competitorn/a
Meas. Tech.ChEMBL_829711
IC50>100000±n/a nM
Citation Gopalakrishnan RKozany CGaali SKress CHoogeland BBracher AHausch F Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52. J Med Chem 55:4114-22 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
FK506 binding protein 4
Name:FK506 binding protein 4
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:51793.87
Organism:Homo sapiens (Human)
Description:ChEMBL_154482
Residue:459
Sequence:
MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW
LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP
KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD
KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN
AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL
EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG
EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE
EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM23334
n/a
NameBDBM23334
Synonyms:3-(pyridin-3-yl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | CHEMBL6367 | GPI 1046
TypeSmall organic molecule
Emp. Form.C20H28N2O4
Mol. Mass.360.4473
SMILESCCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)OCCCc1cccnc1 |r|
Structure
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