| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 2, facilitated glucose transporter member 1 |
|---|
| Ligand | BDBM50388392 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_829819 (CHEMBL2061377) |
|---|
| IC50 | 2000±n/a nM |
|---|
| Citation |  Wang, D; Chu, PC; Yang, CN; Yan, R; Chuang, YC; Kulp, SK; Chen, CS Development of a novel class of glucose transporter inhibitors. J Med Chem55:3827-36 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 2, facilitated glucose transporter member 1 |
|---|
| Name: | Solute carrier family 2, facilitated glucose transporter member 1 |
|---|
| Synonyms: | GLUT-1 | GLUT1 | GTR1_HUMAN | Glucose Transporter 1 (hGLUT1) | Glucose transporter | Glucose transporter type 1, erythrocyte/brain | HepG2 glucose transporter | SLC2A1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 54091.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 492 |
|---|
| Sequence: | MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
ELFHPLGADSQV
|
|
|
|---|
| BDBM50388392 |
|---|
| n/a |
|---|
| Name | BDBM50388392 |
|---|
| Synonyms: | CHEMBL2058262 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H14F9NO3S |
|---|
| Mol. Mass. | 495.359 |
|---|
| SMILES | CC(CN1C(=O)S\C(=C/c2ccc(O)c(c2)C(F)(F)F)C1=O)(CC(F)(F)F)CC(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
