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TargetGlucose Transporter 1 (hGLUT1)
LigandBDBM50388392
Substrate/Competitorn/a
Meas. Tech.ChEMBL_829819
IC50 2000±n/a nM
Citation Wang DChu PCYang CNYan RChuang YCKulp SKChen CS Development of a novel class of glucose transporter inhibitors. J Med Chem 55:3827-36 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Glucose Transporter 1 (hGLUT1)
Name:Glucose transporter
Synonyms:GLUT-1 | Glucose transporter | Glucose transporter type 1, erythrocyte/brain | HepG2 glucose transporter | SLC2A1
Type:Protein
Mol. Mass.:54091.71
Organism:Homo sapiens (Human)
Description:n/a
Residue:492
Sequence:
MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
ELFHPLGADSQV
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  Blast E-value cutoff:
BDBM50388392
n/a
NameBDBM50388392
Synonyms:CHEMBL2058262
TypeSmall organic molecule
Emp. Form.C18H14F9NO3S
Mol. Mass.495.359
SMILESCC(CN1C(=O)S\C(=C/c2ccc(O)c(c2)C(F)(F)F)C1=O)(CC(F)(F)F)CC(F)(F)F
Structure
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