| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM50388819 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_830918 (CHEMBL2065467) |
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| IC50 | 6600±n/a nM |
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| Citation |  Tsuchiya, A; Hirai, G; Koyama, Y; Oonuma, K; Otani, Y; Osada, H; Sodeoka, M Dual-Specificity Phosphatase CDC25A/B Inhibitor Identified from a Focused Library with Nonelectrophilic Core Structure. ACS Med Chem Lett3:294-298 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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| BDBM50388819 |
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| n/a |
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| Name | BDBM50388819 |
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| Synonyms: | CHEMBL2062713 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H45NO5 |
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| Mol. Mass. | 487.6713 |
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| SMILES | CCCCCCCCCCCCCCCC(NCc1ccccc1OC)=C1C(=O)OC(CO)C1=O |w:15.15| |
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| Structure | 
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