Reaction Details | |||
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Target | Cyclin-dependent kinase 1 | ||
Ligand | BDBM50388877 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_830840 (CHEMBL2065346) | ||
Ki | 40±n/a nM | ||
Citation | Milletti, F; Hermann, JC Targeted kinase selectivity from kinase profiling data. ACS Med Chem Lett3:383-386 (2012) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cyclin-dependent kinase 1 | |||
Name: | Cyclin-dependent kinase 1 | ||
Synonyms: | CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase | ||
Type: | Enzyme Subunit | ||
Mol. Mass.: | 34101.08 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P06493 | ||
Residue: | 297 | ||
Sequence: |
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BDBM50388877 | |||
n/a | |||
Name | BDBM50388877 | ||
Synonyms: | CHEMBL2062936 | ||
Type | Small organic molecule | ||
Emp. Form. | C17H18ClN5O | ||
Mol. Mass. | 343.811 | ||
SMILES | O[C@H]1CC[C@@H](CC1)Nc1nc(Cl)cc(n1)-c1c[nH]c2ncccc12 |r,wU:4.7,wD:1.0,(29.96,-30.16,;29.85,-28.62,;29.57,-27.1,;27.75,-27.13,;26.77,-26.34,;27.05,-27.87,;28.79,-27.81,;25.98,-25.03,;26.73,-23.68,;28.27,-23.66,;29.01,-22.3,;30.55,-22.27,;28.22,-20.99,;26.69,-21.02,;25.94,-22.36,;25.9,-19.71,;24.37,-19.57,;24.02,-18.07,;25.34,-17.28,;25.64,-15.76,;27.1,-15.27,;28.26,-16.29,;27.96,-17.79,;26.5,-18.29,)| | ||
Structure |