| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin E |
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| Ligand | BDBM50302107 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_831633 (CHEMBL2064996) |
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| IC50 | 0.8±n/a nM |
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| Citation |  Yang, S; Zhang, W; Ding, N; Lo, J; Liu, Y; Clare-Salzler, MJ; Luesch, H; Li, Y Total synthesis of grassystatin A, a probe for cathepsin E function. Bioorg Med Chem20:4774-80 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin E |
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| Name: | Cathepsin E |
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| Synonyms: | 3.4.23.34 | CATE_HUMAN | CTSE | Cathepsin E form I | Cathepsin E form II |
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| Type: | Enzyme |
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| Mol. Mass.: | 43298.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14091 |
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| Residue: | 396 |
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| Sequence: | MKTLLLLLLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESC
SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF
QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE
FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH
FSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNA
IGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDI
HPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAVP
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| BDBM50302107 |
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| n/a |
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| Name | BDBM50302107 |
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| Synonyms: | CHEMBL567893 | Grassystatin A |
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| Type | Small organic molecule |
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| Emp. Form. | C58H95N9O16 |
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| Mol. Mass. | 1174.4256 |
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| SMILES | COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](OC(=O)[C@@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C)[C@@H](C)O |r| |
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| Structure | 
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