| Reaction Details |
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 | Report a problem with these data |
| Target | Orphan methyltransferase M.SssI |
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| Ligand | BDBM50389499 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_832312 (CHEMBL2066850) |
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| Ki | 250000±n/a nM |
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| Citation |  Plitta, B; Adamska, E; Giel-Pietraszuk, M; Fedoruk-Wyszomirska, A; Naskret-Barciszewska, M; Markiewicz, WT; Barciszewski, J New cytosine derivatives as inhibitors of DNA methylation. Eur J Med Chem55:243-54 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Orphan methyltransferase M.SssI |
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| Name: | Orphan methyltransferase M.SssI |
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| Synonyms: | CpG DNA methylase | M.SssI methyltransferase | MTSI_SPISQ | mssSI | sssIM |
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| Type: | Protein |
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| Mol. Mass.: | 44323.75 |
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| Organism: | Spiroplasma monobiae strain MQ-1 |
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| Description: | P15840 |
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| Residue: | 386 |
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| Sequence: | MSKVENKTKKLRVFEAFAGIGAQRKALEKVRKDEYEIVGLAEWYVPAIVMYQAIHNNFHT
KLEYKSVSREEMIDYLENKTLSWNSKNPVSNGYWKRKKDDELKIIYNAIKLSEKEGNIFD
IRDLYKRTLKNIDLLTYSFPCQDLSQQGIQKGMKRGSGTRSGLLWEIERALDSTEKNDLP
KYLLMENVGALLHKKNEEELNQWKQKLESLGYQNSIEVLNAADFGSSQARRRVFMISTLN
EFVELPKGDKKPKSIKKVLNKIVSEKDILNNLLKYNLTEFKKTKSNINKASLIGYSKFNS
EGYVYDPEFTGPTLTASGANSRIKIKDGSNIRKMNSDETFLYIGFDSQDGKRVNEIEFLT
ENQKIFVCGNSISVEVLEAIIDKIGG
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| BDBM50389499 |
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| n/a |
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| Name | BDBM50389499 |
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| Synonyms: | CHEMBL2063049 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19N3O5 |
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| Mol. Mass. | 321.3285 |
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| SMILES | Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)nc1NCc1ccco1 |r| |
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| Structure | 
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