Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetOrphan methyltransferase M.SssI
LigandBDBM50389505
Substrate/Competitorn/a
Meas. Tech.ChEMBL_832312 (CHEMBL2066850)
Ki 170000±n/a nM
Citation Plitta, BAdamska, EGiel-Pietraszuk, MFedoruk-Wyszomirska, ANaskret-Barciszewska, MMarkiewicz, WTBarciszewski, J New cytosine derivatives as inhibitors of DNA methylation. Eur J Med Chem55:243-54 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Orphan methyltransferase M.SssI
Name:Orphan methyltransferase M.SssI
Synonyms:CpG DNA methylase | M.SssI methyltransferase | MTSI_SPISQ | mssSI | sssIM
Type:Protein
Mol. Mass.:44323.75
Organism:Spiroplasma monobiae strain MQ-1
Description:P15840
Residue:386
Sequence:
MSKVENKTKKLRVFEAFAGIGAQRKALEKVRKDEYEIVGLAEWYVPAIVMYQAIHNNFHT
KLEYKSVSREEMIDYLENKTLSWNSKNPVSNGYWKRKKDDELKIIYNAIKLSEKEGNIFD
IRDLYKRTLKNIDLLTYSFPCQDLSQQGIQKGMKRGSGTRSGLLWEIERALDSTEKNDLP
KYLLMENVGALLHKKNEEELNQWKQKLESLGYQNSIEVLNAADFGSSQARRRVFMISTLN
EFVELPKGDKKPKSIKKVLNKIVSEKDILNNLLKYNLTEFKKTKSNINKASLIGYSKFNS
EGYVYDPEFTGPTLTASGANSRIKIKDGSNIRKMNSDETFLYIGFDSQDGKRVNEIEFLT
ENQKIFVCGNSISVEVLEAIIDKIGG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50389505
n/a
NameBDBM50389505
Synonyms:CHEMBL2063041
TypeSmall organic molecule
Emp. Form.C14H17N3O5
Mol. Mass.307.3019
SMILESOC[C@H]1O[C@H](C[C@@H]1O)n1ccc(NCc2ccco2)nc1=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: