| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 3 |
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| Ligand | BDBM50389592 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_833940 (CHEMBL2072626) |
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| Ki | 1.7±n/a nM |
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| Citation |  Pasternak, A; Feng, Z; de Jesus, R; Ye, Z; He, S; Dobbelaar, P; Bradley, SA; Chicchi, GG; Tsao, KL; Trusca, D; Eiermann, GJ; Li, C; Feng, Y; Wu, M; Shao, Q; Zhang, BB; Nargund, R; Mills, SG; Howard, AD; Yang, L; Zhou, YP Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist. ACS Med Chem Lett3:289-293 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 3 |
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| Name: | Somatostatin receptor type 3 |
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| Synonyms: | SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3) |
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| Type: | Protein |
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| Mol. Mass.: | 45855.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32745 |
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| Residue: | 418 |
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| Sequence: | MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL
GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM
AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV
FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV
WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA
LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE
SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
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| BDBM50389592 |
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| n/a |
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| Name | BDBM50389592 |
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| Synonyms: | CHEMBL2069500 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28N4 |
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| Mol. Mass. | 396.5273 |
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| SMILES | C1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| |
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| Structure | 
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