| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50389798 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_834567 (CHEMBL2072275) |
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| Ki | 34±n/a nM |
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| Citation |  Tosh, DK; Phan, K; Gao, ZG; Gakh, AA; Xu, F; Deflorian, F; Abagyan, R; Stevens, RC; Jacobson, KA; Katritch, V Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening. J Med Chem55:4297-308 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50389798 |
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| n/a |
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| Name | BDBM50389798 |
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| Synonyms: | CHEMBL2070507 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H18N6O4 |
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| Mol. Mass. | 334.3305 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC1CCC1 |r| |
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| Structure | 
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