| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
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| Ligand | BDBM50390017 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_833983 (CHEMBL2072723) |
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| Ki | 45000±n/a nM |
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| Citation |  Costanzi, S; Santhosh Kumar, T; Balasubramanian, R; Kendall Harden, T; Jacobson, KA Virtual screening leads to the discovery of novel non-nucleotide P2Y1 receptor antagonists. Bioorg Med Chem20:5254-61 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 1 |
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| Name: | P2Y purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM50390017 |
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| n/a |
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| Name | BDBM50390017 |
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| Synonyms: | CHEMBL2071537 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17F3N4O4S |
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| Mol. Mass. | 454.423 |
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| SMILES | Cc1noc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccc(cc3)C(F)(F)F)cc2)c1C |
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| Structure | 
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