| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50324086 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_834660 (CHEMBL2072546) |
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| Ki | 1.61±n/a nM |
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| Citation |  Moussa, IA; Banister, SD; Manoli, M; Doddareddy, MR; Cui, J; Mach, RH; Kassiou, M Exploration of ring size in a series of cyclic vicinal diamines withs1 receptor affinity. Bioorg Med Chem Lett22:5493-7 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50324086 |
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| n/a |
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| Name | BDBM50324086 |
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| Synonyms: | CHEMBL1214893 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(3''-fluoropropoxy)benzyl)-piperazine |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27FN2O2 |
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| Mol. Mass. | 382.4711 |
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| SMILES | FCCCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 |
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| Structure | 
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