| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity testis-specific protein kinase 1 |
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| Ligand | BDBM50390779 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_835731 |
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| IC50 | >30000±n/a nM |
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| Citation |  He L; Seitz SP; Trainor GL; Tortolani D; Vaccaro W; Poss M; Tarby CM; Tokarski JS; Penhallow B; Hung CY; Attar R; Lin TA Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett 22:5995-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity testis-specific protein kinase 1 |
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| Name: | Dual specificity testis-specific protein kinase 1 |
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| Synonyms: | TESK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 67696.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_587103 |
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| Residue: | 626 |
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| Sequence: | MAGERPPLRGPGPGPGEVPGEGPPGPGGTGGGPGRGRPSSYRALRSAVSSLARVDDFHCA
EKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGVCV
HQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKN
CLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADV
FAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIHCCNLEPST
RAPFTEITQHLEWILEQLPEPAPLTRTALTHNQGSVARGGPSATLPRPDPRLSRSRSDLF
LPPSPESPPNWGDNLTRVNPFSLREDLRGGKIKLLDTPSKPVLPLVPPSPFPSTQLPLVT
TPETLVQPGTPARRCRSLPSSPELPRRMETALPGPGPPAVGPSAEEKMECEGSSPEPEPP
GPAPQLPLAVATDNFISTCSSASQPWSPRSGPVLNNNPPAVVVNSPQGWAGEPWNRAQHS
LPRAAALERTEPSPPPSAPREPDEGLPCPGCCLGPFSFGFLSMCPRPTPAVARYRNLNCE
AGSLLCHRGHHAKPPTPSLQLPGARS
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| BDBM50390779 |
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| n/a |
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| Name | BDBM50390779 |
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| Synonyms: | CHEMBL2070497 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18Cl2N6OS |
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| Mol. Mass. | 473.378 |
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| SMILES | CCCNc1ncc(s1)-c1cc(nc(n1)-c1cnccn1)-c1c(Cl)cc(OC)cc1Cl |
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| Structure | 
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