| Reaction Details |
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 | Report a problem with these data |
| Target | Translocator protein |
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| Ligand | BDBM50390840 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_835804 (CHEMBL2071915) |
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| Ki | 0.19±n/a nM |
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| Citation |  Wadsworth, H; Jones, PA; Chau, WF; Durrant, C; Morisson-Iveson, V; Passmore, J; O'Shea, D; Wynn, D; Khan, I; Black, A; Avory, M; Trigg, W Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents. Bioorg Med Chem Lett22:5795-800 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Translocator protein |
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| Name: | Translocator protein |
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| Synonyms: | Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo |
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| Type: | Mitochondrion membrane protein |
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| Mol. Mass.: | 18945.84 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competitive binding experiments were performed on rat kidney mitochondrial membranes. |
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| Residue: | 169 |
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| Sequence: | MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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| BDBM50390840 |
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| n/a |
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| Name | BDBM50390840 |
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| Synonyms: | CHEMBL2070786 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23F2NO4 |
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| Mol. Mass. | 427.4405 |
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| SMILES | COc1ccc(OCCF)cc1CN(C(C)=O)c1cc(F)ccc1Oc1ccccc1 |
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| Structure | 
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