| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-binding cassette sub-family C member 2 |
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| Ligand | BDBM50390987 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_839289 (CHEMBL2077960) |
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| Ki | 40000±n/a nM |
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| Citation |  Akhteruzzaman, S; Kato, Y; Hisaka, A; Sugiyama, Y Primary active transport of peptidic endothelin antagonists by rat hepatic canalicular membrane. J Pharmacol Exp Ther288:575-81 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| ATP-binding cassette sub-family C member 2 |
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| Name: | ATP-binding cassette sub-family C member 2 |
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| Synonyms: | ATP-binding cassette sub-family C member 2 | Abcc2 | Canalicular multidrug resistance protein | Canalicular multispecific organic anion transporter 1 | Cmoat | Cmrp | MRP2_RAT | Mrp2 | Multidrug resistance-associated protein 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 173415.22 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1455464 |
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| Residue: | 1541 |
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| Sequence: | MDKFCNSTFWDLSLLESPEADLPLCFEQTVLVWIPLGFLWLLAPWQLYSVYRSRTKRSSI
TKFYLAKQVFVVFLLILAAIDLSLALTEDTGQATVPPVRYTNPILYLCTWLLVLAVQHSR
QWCVRKNSWFLSLFWILSVLCGVFQFQTLIRALLKDSKSNMAYSYLFFVSYGFQIVLLIL
TAFSGPSDSTQTPSVTASFLSSITFSWYDRTVLKGYKHPLTLEDVWDIDEGFKTRSVTSK
FEAAMTKDLQKARQAFQRRLQKSQRKPEATLHGLNKKQSQSQDVLVLEEAKKKSEKTTKD
YPKSWLIKSLFKTFHVVILKSFILKLIHDLLVFLNPQLLKLLIGFVKSSNSYVWFGYICA
ILMFAVTLIQSFCLQSYFQHCFVLGMCVRTTVMSSIYKKALTLSNLARKQYTIGETVNLM
SVDSQKLMDATNYMQLVWSSVIQITLSIFFLWRELGPSILAGVGVMVLLIPVNGVLATKI
RNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRKKELKNLLRFGQLQS
LLIFILQITPILVSVVTFSVYVLVDSANVLNAEKAFTSITLFNILRFPLSMLPMVTSSIL
QASVSVDRLERYLGGDDLDTSAIRRVSNFDKAVKFSEASFTWDPDLEATIQDVNLDIKPG
QLVAVVGTVGSGKSSLVSAMLGEMENVHGHITIQGSTAYVPQQSWIQNGTIKDNILFGSE
YNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYIL
DDPLSAVDAHVGKHIFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGS
YRDLLDKKGVFARNWKTFMKHSGPEGEATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMR
RENSLRRTLSRSSRSSSRRGKSLKNSLKIKNVNVLKEKEKEVEGQKLIKKEFVETGKVKF
SIYLKYLQAVGWWSILFIILFYGLNNVAFIGSNLWLSAWTSDSDNLNGTNNSSSHRDMRI
GVFGALGLAQGICLLISTLWSIYACRNASKALHGQLLTNILRAPMRFFDTTPTGRIVNRF
SGDISTVDDLLPQTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVAT
SRQLRRLDSVTKSPIYSHFSETVTGLPIIRAFEHQQRFLAWNEKQIDINQKCVFSWITSN
RWLAIRLELVGNLVVFCSALLLVIYRKTLTGDVVGFVLSNALNITQTLNWLVRMTSEAET
NIVAVERISEYINVENEAPWVTDKRPPADWPRHGEIQFNNYQVRYRPELDLVLKGITCNI
KSGEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDVASIGLHDLRERLTIIPQDP
ILFSGSLRMNLDPFNKYSDEEVWRALELAHLRSFVSGLQLGLLSEVTEGGDNLSIGQRQL
LCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKI
MVLDNGKIVEYGSPEELLSNRGSFYLMAKEAGIENVNHTEL
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| BDBM50390987 |
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| n/a |
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| Name | BDBM50390987 |
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| Synonyms: | CHEMBL2074660 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H41N5O5 |
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| Mol. Mass. | 527.6556 |
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| SMILES | CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NC(C)CC(O)=O |r| |
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| Structure | 
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