| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-binding cassette sub-family C member 3 |
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| Ligand | BDBM50391004 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_836618 (CHEMBL2077359) |
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| Ki | 83800±n/a nM |
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| Citation |  Akita, H; Suzuki, H; Hirohashi, T; Takikawa, H; Sugiyama, Y Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3. Pharm Res19:34-41 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| ATP-binding cassette sub-family C member 3 |
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| Name: | ATP-binding cassette sub-family C member 3 |
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| Synonyms: | ATP-binding cassette sub-family C member 3 | Abcc3 | Canalicular multispecific organic anion transporter 2 | Cmoat2 | MLP-2 | MRP-like protein 2 | MRP3_RAT | Mlp2 | Mrp3 | Multidrug resistance-associated protein 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 168984.11 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_839340 |
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| Residue: | 1522 |
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| Sequence: | MDRLCGSGELGSKFWDSNLTVYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHR
LGYIVLSCLSRLKTALGVLLWCISWVDLFYSFHGLVHGSSPAPVFFITPLLVGITMLLAT
LLIQYERLRGVRSSGVLIIFWLLCVICAIIPFRSKILLALAEGKILDPFRFTTFYIYFAL
VLCAFILSCFQEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTKLAILGYRRPLEDSDL
WSLSEEDCSHKVVQRLLEAWQKQQTQASGPQTAALEPKIAGEDEVLLKARPKTKKPSFLR
ALVRTFTSSLLMGACFKLIQDLSPSSTHSCSASSSGLFRPHGPYWWGFLLAGLMFVSSTM
QTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMD
VSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMK
FKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCT
PFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRI
QDFLNQDELDPQCVERKTISPGRAITIHNGTFSWSKDLPPTLHSINIQIPKGALVAVVGP
VGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQ
ALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVD
SHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHD
GSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTEPAIYEVRKQFMRE
MSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKS
VGLCTTLFICLLYAGQNAVAIGANVWLSAWTNDVEEHGQQNNTSVRLGVYATLGILQGLL
VMLSAFTMVVGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAP
TILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRS
PIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNC
VVLFSALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSK
TETEAPWVLESNRAPEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRT
GAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLD
PFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSR
VLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFD
SPVNLIAAGGIFYGMAKDAGLA
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| BDBM50391004 |
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| n/a |
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| Name | BDBM50391004 |
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| Synonyms: | CHEMBL213947 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N5O10S |
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| Mol. Mass. | 473.415 |
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| SMILES | N[C@@H](CCC(=O)N[C@H](CSc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O)C(=O)NCC(O)=O)C(O)=O |
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| Structure | 
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